Definition of Diabetes mellitus (DM)



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01- diabetes mellitus rr











Diagnosis of Diabetes Mellitus:
1- Fasting blood glucose level
(normal: 70 – 110 mg/dl)
▪ The patient should be fasting completely 6 hours before test.
▪ Fasting blood glucose level < 110 mg/dl rule out diagnosis of diabetes.
▪ Fasting blood glucose level > 126 mg/dl suggests diabetes mellitus.
2- Two Random blood glucose level
(normal: < 200 mg/dl)
▪ Random blood glucose level > 200 mg/dl suggest diabetes mellitus.
▪ Associated with clinical manifestations of DM (Polyuria, polydipsia & polyphagia)
Impaired Glucose Tolerance (IGT) & Impaired Fasting
Glucose (IFG):
- People with IGT are normoglycemic most of the time but can become hyperglycemic after large glucose loads.
- People with IFG have increased fasting blood glucose levels but usually have normal levels following food consumption.
-
IGT and IFG are risk factors for future diabetes. Approximately 30-40% of individuals with IGT and
IFG will develop type 2 diabetes within 10 years.
- The pathophysiology of IFG and IGT is related primarily to increased insulin resistance whereas endogenous insulin secretion is normal inmost pts. Uncontrolled diabetic
(pseudomembranous candidiasis) Periodontal abscess.



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