Title: Translational Oncology

Title: Translational Oncology

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? Ye, X.P., Bao, S., Guo, L.Y., Wang, X.H., Ma, Y.P., Zhang, W., Wang, C.H., Zhang, Y.F., Zhi, F., Gao, Y., Tian, J.H., Li, R. and Gao, H.M. (2013), Accelerated partial breast irradiation for breast cancer: A meta-analysis. Translational Oncology, 6 (6), 619-627.

Full Text: 2013\Tra Onc6, 619.pdf

Abstract: To evaluate the long-term effect of breast conservation with accelerated partial breast irradiation (APBI) for early-stage breast cancer, PubMed, EMBASE, Cochrane Library, Web of Science, Chinese Biomedical Literature Database, Chinese Scientific Journals Full-text Database, and China Journal Full-text Database were searched to identify relevant original published trials. Randomized controlled trials in any language comparing APBI with whole-breast radiotherapy in patients with early-stage breast cancer were included. RevMan 5 software was used for statistical analysis. Four trials involving 919 patients were included. The rate of 5- and 7-year excellent/good cosmetic results was significant {odds ratio (OR) = 2.09 [95% confidence interval (CI) = 1.21-3.62]} between two groups. The 5-and 8-year overall survival had no significant difference [OR = 1.76 (95% CI = 0.67-4.62) and OR = 0.86 (95% CI = 0.44-1.66)]. The 10-year overall survival had significant differences [OR = 0.56 (95% CI = 0.35-0.91)]. There were no differences in the 5-year local recurrence (LR)-free survival [OR = 0.65 (95% CI = 0.18-2.34)], cancer-specific survival [OR = 1.67 (95% CI = 0.39-7.12)], disease-free survival [OR = 0.84 (95% CI = 0.38-1.84)], LR [OR = 1.36 (95% CI = 0.46-3.99)], the rate of contralateral breast cancer [OR = 2.82 (95% CI = 0.73-10.89)], and distant metastasis [OR = 0.71 (95% CI = 0.22-2.31)]. APBI significantly improved the rate of excellent/good cosmetic results anywhere in the breast, shortened the treatment time, alleviated the pain, and improved the quality of life. Future large-scale, high-quality, and double-blind trials are needed.

Keywords: Analysis, Biomedical, Breast Cancer, Cancer, China, Chinese, Confidence, Conservation, Database, Double-Blind, Embase, Groups, Interval, Irradiation, Journal, Journals, Language, Life, Literature, Local, Long Term, Long-Term, Metastasis, Pain, Patients, Pubmed, Quality, Quality Of, Quality of Life, Radiotherapy, Randomized Controlled Trials, Recurrence, Science, Scientific Journals, Software, Statistical Analysis, Survival, Treatment, Web of Science

Title: Transplant International

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? Lai, Q., Darius, T. and Lerut, J. (2012), The one hundred most frequently cited articles in the field of clinical liver transplantation. Transplant International, 25 (6), e76-e77.

Full Text: 2012\Tra Int25, e76.pdf

Keywords: Articles, Clinical, Field, Journals, Liver, Liver Transplantation, SI, Transplantation

Title: Transplantation

Full Journal Title: Transplantation

ISO Abbreviated Title: Transplantation

JCR Abbreviated Title: Transplantation

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? Kortram, K., Lafranca, J.A., IJzermans, J.N.M. and Dor, F.J.M.F. (2014), The need for a standardized informed consent procedure in live donor nephrectomy: A systematic review. Transplantation, 98 (11), 1134-1143.

Full Text: 2014\Transplantation98, 1134.pdf

Abstract: Background. Informed consent in live donor nephrectomy is a topic of great interest. Safety and transparency are key items increasingly getting more attention from media and healthcare inspection. Because live donors are not patients, but healthy individuals undergoing elective interventions, they justly insist on optimal conditions and guaranteed safety. Although transplant professionals agree that consent should be voluntary, free of coercion, and fully informed, there is no consensus on which information should be provided, and how the donors’ comprehension should be ascertained. Methods. Comprehensive searches were conducted in Embase, Medline OvidSP, Web-of-Science, PubMed, CENTRAL (The Cochrane Library 2014, issue 1) and Google Scholar, evaluating the informed consent procedure for live kidney donation. The methodology was in accordance with the Cochrane Handbook for Interventional Systematic Reviews and written based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results. The initial search yielded 1,009 hits from which 21 articles fell within the scope of this study. Procedures vary greatly between centers, and transplant professionals vary in the information they disclose. Although research has demonstrated that donors often make their decision based on moral reasoning rather than balancing risks and benefits, providing them with accurate, uniform information remains crucial because donors report feeling misinformed about or unprepared for donation. Although a standardized procedure may not provide the ultimate solution, it is vital to minimize differences in live donor education between transplant centers. Conclusion. There is a definite need for a guideline on how to provide information and obtain informed consent from live kidney donors to assist the transplant community in optimally preparing potential donors.

Keywords: Advocate, Articles, Attention, Benefits, Coercion, Community, Consensus, Consent, Decision, Donor, Donor Education, Educate, Education, Elective, Ethical-Issues, Europe, From, Google, Google Scholar, Guideline, Guidelines, Incentives, Information, Informed Consent, Inspection, Interventions, Kidney, Live, Live Donor Nephrectomy, Live Kidney Donation, Living Kidney Donors, Media, Medline, Methodology, Methods, Nephrectomy, Optimal Conditions, Organ Donation, Patients, Potential, Procedure, Pubmed, Reasoning, Research, Results, Review, Risks, Safety, Scope, Solution, Systematic, Systematic Review, Systematic Reviews, Topic, Transparency, Transplantation, Vary, Web Of Science

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