Let us help you simplify the complex!



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Let us help you simplify the complex!

PSSC is the government approved resource to empower stakeholders to achieve integrity, access, and value from the 340B Program.
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Do you have questions?

PSSC has answers!





  • How do I know which patients qualify for 340B?


  • I think our clinic is being overcharged for a medicine, what do I do?


  • Can you explain how contract pharmacy is supposed to work?




PSSC Call Center

A FREE resource to help with all of your 340B inquiries. Staff, trained in the various issues relating to the 340B Program, is on hand to answer questions or direct your calls to the appropriate people. Call 800-628-6297, Monday through Friday, from 9:00 a.m. to 4:30 p.m. (Eastern Time), or email PSSC@aphanet.org.






  • What pharmacy option is right for us?


  • Is our program 340B compliant?


  • Can you recommend cost containment strategies for our program?




PSSC PharmTA

A FREE, government approved resource providing 340B-eligible entities solutions directly from expert pharmacist consultants. An objective-based work plan guides the process, and TA is delivered via phone, email or site visit. Contact PSSC at 800-628-6297 or PSSC@aphanet.org to request this service.



Quick Facts....



  • The 340B Drug Pricing Program requires manufacturers participate in Medicaid to sell outpatient drugs to specific safety net healthcare providers including certain hospitals, community health centers, and others, at a deeply discounted price.

  • The 340B price averages between 20-50% below the Average Wholesale Price.

  • After applying to the Office of Pharmacy Affairs (OPA) for participation in the 340B program, covered entities can begin taking advantage of these low prices at the start of the next quarter.

What PSSC Clients are Saying...

"My interaction with this group involved a quick, complete and precise response to my inquiry. I could not ask for more."

"Your service is a life saver! Thanks again for all your help!"

"I could not ask for anyone more pleasant, helpful and sincerely interested in making sure all my questions were answered to my satisfaction. You obviously hire exceptional employees."

Visit http://pssc.aphanet.org or call 800-628-6297 for more information. Look for us on Linked in: search for the “340B Resource Network” and join our group today!

About the HRSA Pharmacy Services Support Center

The Health Resources and Services Administration (HRSA) Pharmacy Services Support Center (PSSC) operates through the American Pharmacists Association (APhA) to help federally funded clinics and other health care safety net providers develop clinically and cost effective pharmacy services. Central to this endeavor is optimal use of the 340B Drug Pricing Program, which is run by the Office of Pharmacy Affairs (OPA) in the HRSA Healthcare Systems Bureau. PSSC provides free information, education, and technical assistance to increase patient access to affordable drugs and pharmacy services.

What is the 340B Drug Pricing Program?

The 340B Drug Pricing Program requires manufacturers to sell outpatient drugs to specific safety net healthcare providers including certain hospitals, community health centers, HIV/AIDS clinics and others, at a price discounted at least as much as dictated by the 340B statute. The 340B price is at least as low as the price that state Medicaid agencies currently pay and averages 20-50% below the Average Wholesale Price. After applying to the Office of Pharmacy Affairs (OPA) for participation in the 340B program, covered entities can begin taking advantage of these low prices at the start of the next quarter. Application deadlines follow:

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The Office of Pharmacy Affairs (OPA)

The OPA was created in 1992 as a result of the federal legislation that implemented the 340B Drug Pricing Program. OPA has three primary functions.

1) OPA Administers the 340B Drug Pricing Program.

2) OPA develops innovative pharmacy service models and provision of technical assistance to help entities implement effective pharmacy programs.

3) OPA serves as a federal resource about pharmacy.

For more information on the OPA, visit www.hrsa.gov/opa or call 800-628-6297.

The Best Chance for Even More Savings—the 340B Prime Vendor Program

On Sept. 10, 2004, HRSA’s Office of Pharmacy Affairs awarded a direct contract to Provista (formerly HealthCare Purchasing Partners International) to serve as the Prime Vendor for the 340B Program. Provista formed a nonprofit subsidiary corporation, Apexus, Inc., to manage the 340B Prime Vendor Program. The purpose of the program is to improve access to affordable outpatient medications for covered entities and their patients by implementing drug distribution solutions and securing sub-340B pricing on products for program participants. To learn more about the 340B Prime Vendor Program, visit www.340bpvp.com or call 888-340-2787.

Contact Us



Call 800-628-6297, email PSSC@aphanet.org, visit http://pssc.aphanet.org.

HRSA PSSC, American Pharmacists Association, 2215 Constitution Ave., NW Washington, DC 20037-2985. PSSC provides information, education, and policy analysis to help eligible entities optimize the value of the 340B program and provide clinically and cost effective pharmacy services that improve medication use and advance patient care.

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