A review of ssri-induced indifference


Hoehn-saric et al.29 1990



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Hoehn-saric et al.29 1990

Apathy and indifference in patients on fluvoxamine and fluoxetine

Case reports

Apathy observed among 5 patients receiving fluvoxamine and fluoxetine with effects rapidly disappearing when dose of fluvoxamine reduced, with fluoxetine dose reduction having less effect.

Monga, Padala et al.30 2015

Aripiprazole as treatment for apathy

Case report

42-year-old man with depression and seizure disorder had significant apathy assessed on Apathy Evaluation Scale, improved significantly on Aripiprazole 15 mg/day

Bertschy et al.31 1995

Vulnerability to fluoxetine-induced indifference

Case Report

3 cases of reports of feeling emotionally indifferent in patients receiving methadone with resolution of the symptoms upon discontinuing fluoxetine.


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