rats
[195]
|
Daglioglu et al.
|
2009
|
experimental peripheral nerve injury
|
sciatic nerve
|
50 mg/kg (x4)
|
rats
|
[196]
|
Sirajudeen et al.
|
2011
|
aflatoxin B1-induced oxidative damage
|
liver & plasma
|
40 mg/kg
|
chicken
|
[197]
|
Saxena et al.
|
2010
|
intracerebroventricular administration of streptozotocin-induced memory deficit
|
brain
|
2.5 to 10 mg/kg
|
rats
|
[198]
|
Sönmez et al.
|
2009
|
alcohol-induced oxidative stress
|
aorta
|
4 mg/kg
|
rats
|
[199]
|
Jou et al.
|
2010
|
ROS-induced mitochondrial damage
|
brain
|
100 µM
|
rats
|
[200]
|
Hoppe et al.
|
2010
|
amyloid-beta neurotoxicity
|
hippocampal slice cultures
|
25 to 100 µM
|
rats
|
[201]
|
Guo et al.
|
2010
|
ischemia/reperfusion injury
|
N2a cells
|
100 µM
|
mice
|
[202]
|
Mukherjee et al.
|
2010
|
isoproterenol-induced injury
|
Heart
|
10 mg/kg
|
rats
|
[203]
|
Rao et al.
|
2010
|
mercury-exerted neurotoxicity
|
Brain
|
5 mg/kg
|
rats
|
[204]
|
Lekic et al.
|
2010
|
intracerebral hemorrhage-induced damages
|
Brain
|
5 mg/kg
|
rats
|
[205]
|
Oliveira et al.
|
2010
|
Trypanosoma cruzi infection
|
Serum
|
5 mg/kg
|
rats
|
[206]
|
Wang et al.
|
2011
|
ischemia/reperfusion-induced mitochondrial dysfunction
|
isolated muscle
|
10 mg/kg
|
rats
|
[207]
|
Tripathi & Jena
|
2010
|
cyclophosphamide-induced injury
|
Bladder
|
10 mg/kg
|
rats
|
[208]
|
Domínguez-Rebolledo et al.
|
2010
|
thawing-induced fragility
|
Sperm
|
0.1 to 1 mM
|
rein deer
|
[209]
|
Ganguly et al.
|
2010
|
indomethacin-induced gastric ulcer
|
Stomach
|
80 mg/kg
|
mice
|
[210]
|
Aranda et al.
|
2010
|
carbon tetrachloride toxicity
|
Liver
|
10 mg/kg
|
rats
|
[211]
|
Romero et al.
|
2010
|
rotenone and oligomycin-A -induced oxidative stress
|
SH-SY5Y neuroblastoma cells
|
0.3-10 nM
|
human cells
|
[212]
|
Aydemir et al.
|
2010
|
adriamycin-induced toxicity
|
Heart
|
5mg/kg
|
rats
|
[213]
|
Patel et al.
|
2010
|
isoproterenol-induced infarction
|
Heart
|
10 mg/kg
|
rats
|
[214]
|
Pant & Rao
|
2010
|
arsenic and fluoride-induced genotoxicity
|
peripheral blood cell culture
|
0.2 mM
|
human
|
[215]
|
Ozturk et al.
|
2011
|
doxorubicin- and trastuzumab-induced toxicity
|
Heart
|
10 mg/kg (x2)
|
rats
|
[216]
|
Negi et al.
|
2011
|
diabetic neuropathy-induced neuroinflammation and oxidative stress
|
Nerves
|
3 to 10 mg/kg
|
rats
|
[217]
|
Zhao et al.
|
2011
|
cryopreservation
|
Callus
|
100 nM
|
Rhodiola crenulata
|
[218]
|
Jaworek et al.
|
2010
|
caerulein-induced pancreatitis
|
Pancreas
|
5 to 25 mg/kg
|
rats
|
[219]
|
Han et al.
|
2011
|
injury-evoked nitrosative stress
|
endothelial cells
|
10 µM
|
human cells
|
[220]
|
Ionov et al.
|
2011
|
beta-amyloid neurotoxicity
|
neuron and astrocytes mixed cultures
|
50 µM
|
rats
|
[221]
|
Jou
|
2011
|
mitochondrial Ca(2+) stress in astrocyte
|
Astrocytes
|
100 µM
|
rat cells
|
[222]
|
Espino et al.
|
2011
|
intracellular calcium overload-induced apoptosis
|
Leukocytes
|
1 mM
|
human cells
|
[223]
|
Dayoub et al.
|
2011
|
endothelial cell damage induced by lipopolysaccharide
|
endothelial cells
|
100 µM
|
human cells
|
[224]
|
Anjum et al.
|
2011
|
bisphenol A-induced biochemical toxicity
|
Testis
|
10 mg/kg
|
mouse
|
[225]
|
Zhou et al.
|
2012
|
rotenone-induced cell injury
|
HeLa cells
|
250 μM
|
human cells
|
[226]
|
Wang et al.
|
2011
|
Huntingtin-mediated toxicity
|
neuronal cells
|
5 µM
|
rats
|
[207]
|
Singh et al.
|
2011
|
experimental reflux
|
Œsophage
|
20 to 40 mg/kg
|
mice
|
[227]
|
Ono et al.
|
2012
|
α-synuclein cytotoxicity
|
neuronal cells
|
25 to 2500 µM
|
in vitro
|
[228]
|
Shirazi et al.
|
2013
|
irradiation-induced oxidative damage
|
blood cells
|
10 mg/kg
|
rats
|
[229]
|
Fu et al.
|
2012
|
apoptosis
|
retinal pigment epithelial cells
|
0.1 to 100 µM
|
human cells
|
[230]
|
Celinski et al.
|
2011
|
Helicobacter pylori infection-induced ulcers
|
stomach & duodenum
|
5 mg (x2)
|
Human
|
[231]
|
Sönmez et al.
|
2012
|
alcohol-induced oxidative stress
|
Kidney
|
4 mg/kg
|
rats
|
[232]
|
Kunak et al.
|
2012
|
mechlorethamine-induced toxicity
|
Kidney
|
100 mg/kg
|
rats
|
[233]
|
Arguelles et al.
|
2012
|
lipid peroxidation-induced elongation factor-2 decline
|
HeLa cells
|
10 to 50 µM
|
human cells
|
[234]
|
Cheshchevik et al.
|
2012
|
carbon tetrachloride-induced intoxication
|
Liver
|
10 mg/kg (x30)
|
rats
|
[235]
|
Qin et al.
|
2012
|
IL1β-induced MMP9 expression
|
endothelial cells
|
10 µM
|
human cells
|
[236]
|
Ganguly et al.
|
2012
|
Chronic indomethacin ulceration-induced MMP-3 and MMP-9 augmentation
|
gastric tissues
|
40 mg/kg
|
mice
|
[237]
|
Mukherjee et al.
|
2012
|
isoproterenol-induced alterations
|
Heart
|
10 mg/kg
|
rats
|
[238]
|
Bekyarova et al.
|
2012
|
burn-induced injury
|
Liver
|
10mg/kg
|
rats
|
[239]
|
Yip et al.
|
2013
|
stem cell therapy for acute lung ischemia-reperfusion injury
|
Lung
|
20 & 50 (x2) mg/kg
|
rats
|
[240]
|
Ali et al.
|
2012
|
Hypoxia
|
Liver
|
10 mg/kg
|
rats
|
[241]
|
Kireev et al.
|
2013
|
ischemia/reperfusion-induced cellular injury
|
Liver
|
10 mg/kg
|
rats
|
[242]
|
Canonico et al.
|
2013
|
UVB-exposed-induced mitochondrial injuries
|
U937 cells
|
1 mM
|
human cells
|
[243]
|
Espino et al.
|
2013
|
TNF-α-induced apoptosis
|
Leukocytes
|
1 mM
|
human cells
|
[244]
|
Yawno et al.
|
2013
|
hypoxia-induced fetal insult
|
Brain
|
2 mg
|
sheep
|
[245]
|
Ferreira et al.
|
2013
|
cyclophosphamide-induced DNA damage
|
bone marrow cells
|
1 mg/kg (x15)
|
rats
|
[246]
|
Konturek et al.
|
2013
|
reflux esophagitis
|
esophage
|
20 mg/kg
|
rats
|
[247]
|
Bai et al.
|
2013
|
apoptosis-induced insults
|
lens
|
10 nM to 10 µM
|
humans
|
[248]
|
Zasada et al.
|
2013
|
nitrobenzene-induced lipid peroxidation
|
thyroid
|
1 nM to 7.5 mM
|
pigs
|
[249]
|
Lee et al.
|
2014
|
sarcopenia (indirect)
|
muscles
|
natural levels
|
humans
|
[250]
|
Yang et al.
|
2013
|
ischemia/reperfusion injury
|
isolated heart
|
5 µM
|
rats
|
[251]
|
Sayyed et al.
|
2013
|
inflammation-related disorders
|
gastrointestinal tract
|
10 mg/kg (x 15)
|
rats
|
[252]
|
Chen et al.
|
2014
|
subarachnoid hemorrhage-induced injury
|
brain
|
150 mg/kg
|
rats
|
[253]
|
Karamian et al.
|
2013
|
diazinon-induced genotoxicity
|
lymphocytes
|
100 to 400 µM
|
human cells
|
[254]
|
Drury et al.
|
2014
|
Asphyxia
|
several organs
|
0.1 mg/kg (x 8)
|
sheep
|
[255]
|
Macit et al.
|
2013
|
nitrogen mustard-induced toxicity
|
lung
|
100 mg/kg
|
rats
|
[256]
|
Hrenak et al.
|
2013
|
doxorubicin-induced toxicity
|
kidneys
|
10 mg/kg (x28)
|
rats
|
[257]
|
Parada et al.
|
2014
|
ischemia-induced oxidative stress
|
hippocambal cultures
|
0.1 to 10 µM
|
mice
|
[258]
|
Pinato et al.
|
2013
|
intracerebroventricular LPS-induced acute neuroinflammation
|
brain
|
natural concentration
|
rats
|
[259]
|
Katkar et al.
|
2014
|
Echis carinatus venom-induced toxicities
|
whole animals
|
200 mg/kg
|
mice
|
[260]
|
San-Miguel et al.
|
2014
|
rabbit hemorrhagic disease virus-induced failure
|
liver
|
20 mg/kg (x3)
|
rabbits
|
[261]
|
Wong et al.
|
2014
|
