Monday AM
OPENING SESSION
Clyde Auditorium
07:45 - 08:20
Welcome and Medal Presentations
Robert R. Edelman, President, ISMRM
Carlo Bartolozzi, President, ESMRMB
FIFTH ANNUAL LAUTERBUR LECTURE
Clyde Auditorium
08:20 - 09:00
From the Genome to Molecular Imaging: Dream or Reality?
George K. Radda
Medical Research Council
London, England, UK
PLENARY LECTURES
New Contrast Agents
Clyde Auditorium
09:00 - 10:15
Chairs: Jeffrey L. Evelhoch
P.V. Prasad
Educational Objectives
Upon completion of this session, participants should be able to
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List examples of specific molecular targets which fluorescent probes can be used to identify and/or quantify.
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Identify approaches that are being used to develop MR contrast agents which can be used to identify and/or quantify specific molecular targets.
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Explain how a MR contrast agent can be activated by an enzyme.
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Compare and contrast the advantages and disadvantages of fluorescent probes and MR contrast agents for identifying specific molecular targets.
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Predict what role targeted MR contrast agents will play in future clinical practice.
9:00
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1.
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Imaging Fluorescent Probes in Living Cells, Tissues and Animals.
Stephen R. Adams
University of California, San Diego, La Jolla, CA, USA
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9:25
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2.
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Affinity-Targeted Contrast Agents
Samuel A. Wickline, Gregory M. Lanza
Washington University School of Medicine, Saint Louis, MO, USA
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9:50
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3.
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Seeing is Believing: Visualizing In Vivo Gene Expression and Secondary Messengers by MRI
Thomas J Meade
California Institute of Technology, Pasadena, CA, USA
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Image Reconstruction Methods
Clyde Auditorium
11:00 - 13:00
Chairs: James G. Pipe
E. Mark Haacke
11:00
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4.
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Young Investigator Awards Finalist: Advances in Sensitivity Encoding with Arbitrary k-Space Trajectories
Klaas Paul Pruessmann1, Markus Weiger1, Peter Börnert2, Peter Boesiger1
1ETH and University Zurich, Zurich, Switzerland; 2Philips Research, Hamburg, Germany.
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11:20
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5.
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Young Investigator Awards Finalist: Unifying Linear Prior-information-driven Methods for Accelerated Image Acquisition — Development of a Broad-use Linear Acquisition Speed-up Technique (BLAST) to Overcome Existing Limitations
Jeffrey Tsao1, Babak Behnia1, Andrew Webb1
1University of Illinois at Urbana-Champaign, Urbana, IL USA.
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11:40
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6.
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Sum-of-Squares Image Reconstruction with SMASH
Michael A. Ohliger1, Charles A. McKenzie1, Ernest N. Yeh1, Mark D. Price1, Daniel K. Sodickson1
1Beth Israel Deaconess Medical Center, Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA USA.
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11:52
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7.
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New Approaches to Self-Calibrating Parallel Imaging
Charles A. McKenzie1, Mark D. Price1, Ernest N. Yeh1, Michael A. Ohliger1, Daniel K. Sodickson1
1Beth Israel Deaconess Medical Center, Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA USA.
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12:04
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8.
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Push-button PPA Reconstructions: GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA)
Mark Griswold1, Peter Jakob1, Robin Heidemann1, Mathias Nittka1, Jianmin Wang2, Berthold Kieffer2
1Universität Würzburg, Würzburg, Germany; 2Siemens Medical Engineering, Erlangen, Germany.
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12:16
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9.
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FUSION for Incremental Field-of-View Imaging
Yudong Zhu1
1GE Corporate R&D Center, Niskayuna, NY, USA.
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12:28
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10.
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Dynamic Imaging by Temporal Modeling with Principal Component Analysis
Ananya Sen Gupta1, Zhi-Pei Liang1
1University of Illinois at Urbana-Champaign, Urbana, IL USA.
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12:40
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11.
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Establishing T2-Contrast in True FISP Imaging
Robin Heidemann1, Mark Griswold1, Claudia Hillenbrand1, Dietbert Hahn2, Axel Haase1, Peter Jakob1
1Universität Würzburg, Würzburg, Germany; 2Institut für Röntgendiagnostik, Würzburg, Germany.
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RF Coil Design and Applications
Lomond
11:00 - 13:00
Chairs: Christopher M. Collins
Helmut Merkle
11:00
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12.
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A Four Channel Transceive Phased Array Head Coil for 3T
Scott B. King1, Randy Duensing2, Stephen Varosi3, David Peterson4, David A. Molyneaux4
1MRI Devices Corporation, Gainesville, FL USA.; 2Applied Resonance Technology, Inc., Gainesville, FL, USA ; 3University of Florida, Applied Resonance Technology, Inc., Gainesville, FL, USA ; 4MRI Devices Corporation, Gainesville, FL, USA.
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11:12
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13.
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A Large Volume Four-Ring Birdcage Transmit/Receive Coil for 3.0 T Head Imaging
Labros Petropoulos1, Joseph Murphy-Boesch1
1USA Instruments, Aurora, OH, USA.
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11:24
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14.
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Open-Face Quadrature "Birdcage" Head Coil
Hiroyuki Fujita1, William O. Braum2, Gordon Demeester3
1USA Instruments, Inc., Aurora, OH, USA; 2Marconi Medical Systems, Cleveland, OH, USA; 3Wickliffe, OH, USA.
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11:36
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15.
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The Head Cradle: An Open Faced, High Performance TEM Coil
J. Thomas Vaughan1, Gregor Adriany1, Michael Garwood1, Peter Andersen1, Kamil Ugurbil1
1The University of Minnesota, Center for Magnetic Resonance Research, Minneapolis, MN, USA;
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11:48
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16.
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Design of Planar Strip Array for MRI
Ray Lee1
1General Electric Co., Corporate Research & Development Center, Niskayuna, NY, USA.
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12:00
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17.
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Ladder Networks for Capacitive Decoupling in Phased-Array Coils *
Jovan Jevtic1
1IGC-Medical Advances Inc., Milwaukee, WI, USA.
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12:12
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18.
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Arrays of Birdcage Coils for Imaging Multiple Samples
Steven M. Wright1, Mary McDougall1, David G. Brown1, John Hazle2
1Texas A&M University, College Station, TX, USA; 2University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
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12:24
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19.
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Two Methods for Multi-Sample Imaging: Applications to Mouse Phenotyping via MRI
H. Douglas Morris1, Scott Chesnick1
1National Institutes of Health, Bethesda, MD, USA.
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12:36
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20.
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Varactor Tuned Flexible Interventional Receiver Coils
Greig Scott1, Garry E. Gold1
1Stanford University, Stanford, CA, USA.
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12:48
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21.
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Concentric Coil Arrays for Spatial Encoding in Parallel MRI
Michael A. Ohliger1, Robert Greenman1, Charles A. McKenzie1, Daniel K. Sodickson1
1Beth Israel Deaconess Medical Center, Boston, MA, USA.
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CLINICAL CATEGORICAL COURSE
Cardiac MR Imaging
Hall 2
11:00 - 13:00
Chairs: Zahi A. Fayad
Christopher M. Kramer
Educational Objectives: Upon completion of this course, participants should be able to
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Describe basic areas of routine and promising use of clinical MR in assessing cardiovascular disease.
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Describe methodology and interpret results for MR assessment of acquired and congenital heart disease.
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Apply MR protocols for the evaluation of cardiac morphology, function, viability, and blood flow.
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Compare approaches for optimal presentation and analysis of cardiac MR results.
11:00 Introduction
Dudley J. Pennell
11.25 Congenital Heart Disease
Albert de Roos
11:50 MR Coronary Angiography
John N. Oshinski
12:15 Atherosclerotic Plaque Characterization
Zahi A. Fayad
12:40 Discussion
fMRI Data Analysis
Hall 5
11:00 - 13:00
Chairs: Mark J. Lowe
James J. Pekar
11:00
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22.
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Physiological Noise Reduction in fMRI Using Vessel Time-Series as Covariates in a General Linear Model
Torben Lund1, Lars Hanson1
1Hvidovre Hospital, Hvidovre, Denmark.
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11:12
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23.
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Detection Of Time Windows Of Brain Responses in fMRI Using Modified Temporal Clustering Analysis
Seong-Hwan Yee1, Trevor Andrews1, Jia-Hong Gao1
1University of Texas Health Science Center at San Antonio, San Antonio, TS, USA.
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11:24
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24.
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Spatial & Temporal Independent Component Analysis of fMRI Data with Two Task-Related Waveforms
James J. Pekar1, Vince Calhoun2, Tulay Adali3, Godfrey D. Pearlson2
1Kennedy Krieger Institute & Johns Hopkins University, Baltimore, MD, USA; 2Johns Hopkins University, Baltimore, MD, USA; 3University of Maryland Baltimore County, Baltimore, MD, USA.
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11:36
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25.
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The Use of Spatio-Temporal Properties to Detect Activation in Event-Related fMRI Data
Shing-Chung Ngan1, William Auffermann1, Shantanu Sarkar1, Xiaoping Hu1
1University of Minnesota, Minneapolis, MN, USA.
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11:48
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26.
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Simulation Studies on the Performance of Independent Component Analysis in Analyzing fMRI Data with Transient, Randomly Occurring Events
Hong Gu1, Hanhua Feng1, Wang Zhan2, Su Xu1, David A. Silbersweig1, Emily Stern1, Yihong Yang2
1Weill Medical College of Cornell University, New York, NY, USA; 2Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
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12:00
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27.
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Using the Cortical Surface Information for the Detection of fMRI Activation Signal
Jean-Baptiste Poline1, Alexandre Andrade1, Ferath Kherif1, Stephane Bahrami1, Isabelle Klein1, Jean-Francois Mangin1, Keith J. Worsley2, Denis Le Bihan1
1SHFJ Commissariat a l'Energie Atomique, Orsay, France; 2McGill University, Montreal, Canada.
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12:12
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28.
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Suppresion of Non-Capillary BOLD Signals Through The Use Of Phase Fluctuations
Ravi S. Menon1
1The John P. Robarts Research Institute, London, ON, Canada.
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12:24
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29.
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Ballistocardiogram Removal and Motion Correction for EEG in the Magnet
Patrick L. Purdon1, Iiro P. Jaaskelainen1, Victor Solo2, Emery N. Brown3, John W. Belliveau1, Giorgio Bonmassar1
1Massachusetts General Hospital, NMR Center, Charlestown, MA, USA; 2University of New South Wales, Sydney, NSW, Australia; 3Massachusetts General Hospital, Boston, MA, USA.
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12:36
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30.
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Resting State Neurovascular Fluctuation At Different States Of Conciousness.
Vesa Johannes Kiviniemi1, Juha-Pekka Kantola1, Bharat Biswal2, Osmo Tervonen1, Jukka Jauhiainen1
1Oulu University Hospital, Oulu, Finland; 2Medical College of Wisconsin, Milwaukee, WI, USA.
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12:48
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31.
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Frequencies Contributing to Functional Connectivity in the Cerebral Cortex in "Resting-State" Data
Dietmar Cordes1, V.M Haughton1, Konstantinos Arfanakis1, J.D Carew1, P.A Turski1, C.H Moritz1, M.A Quigley1, M.E Meyerand1
1University of Wisconsin-Madison, Madison, WI, USA.
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MR Imaging of Articular Cartilage
Hall 1
11:00 - 13:00
Chairs: Garry E. Gold
Douglas W. Goodwin
11:00
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32.
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Comparison of dGEMRIC and T2 Imaging of Articular Cartilage
Nina M. Menezes1, Martha L. Gray2, Deborah Burstein3
1Massachusetts Institute of Technology, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2Massachusetts Institute of Technology, Cambridge, MA, USA; 3Beth Israel Deaconess Medical Center, Boston, MA,USA.
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11:12
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33.
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GdDTPA2--enhanced T1 Imaging of Proteoglycans Predicts Cartilage Stiffness in Bovine Humeral Head
Miika T Nieminen1, Juha Töyräs2, Mikko S Laasanen2, Jarno Rieppo1, Johanna Silvennoinen3, Heikki J Helminen1, Jukka S Jurvelin2
1University of Kuopio, Kuopio, Finland; 2Kuopio University Hospital, Kuopio, Finland; 3A.I.Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland.
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11:24
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34.
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Relaxivity of Gadolinium Agents in Cartilage at 2T: Effects on dGEMRIC Imaging
Amy M. Gillis1, Martha Gray1, Deborah Burstein1
1Beth Israel Deaconess Medical Center, Boston, MA, USA.
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11:36
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35.
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Magnetic Resonance Imaging of Porcine Articular Cartilage before and after Cryopreservation
L. Laouar1, K. Fishbein2, N. Jomha1, L. E. McGann1, R.G.S. Spencer2
1University of Alberta, Edmonton, Alberta, Canada; 2National Institutes of Health, Baltimore, MD, USA.
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11:48
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36.
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Cartilage Anisotropic Deformation Yields a Dual Role for Proteoglycan Content
Jonathan Kaufman1, Umamaheswar Duvvuri1, Ravinder Regatte1, Ravinder Reddy1, John S. Leigh1
1University of Pennsylvania, Philadelphia, PA, USA.
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12:00
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37.
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In Vivo Assessment Of Proteoglycan Loss In The Articular Cartilage Of The Goat Knee With Gadolinium-Enhanced MRI After Papain Injection
Didier Laurent1, James Wasvary1, Jianyun Yin1, Hem Nalini Singh1, Gary Pastor1, Vincent Blancuzzi1, Elizabeth O'Byrne1, Theodore Pellas1
1Novartis Pharmaceuticals Corporation, Summit, NJ, USA.
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12:12
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38.
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Multinuclear MRI Evauation of Cartilage Degeneration
Erik M. Shapiro1, Arijitt Borthakur1, Jonathan Kaufman1, John S. Leigh1, Ravinder Reddy1
1University of Pennsylvania, Philadelphia, PA, USA.
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12:24
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39.
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Measurement of Cartilage's Internal Elastic Properties Using MR Elastography
Anne C. Ridler, Don B. Plewes, and R. Mark Henkelman1
1University of Toronto, Sunnybrook and Women's College Health Sciences Center, Toronto, Ontario, Canada;
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12:36
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40.
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Vertical Striations in the Radial Layer of MR Images of Hyaline Cartilage are due to T2 Effects
Goodwin D.W.1, Hao Lei1, J. F. Dunn1
1Dartmouth Medical School, Hanover, NH, USA.
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12:48
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41.
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Assessment Of Collagen Integrity In Articular Cartilage By Using Magnetization Transfer Imaging: In Vivo Application To The Goat Knee
Didier Laurent1, James Wasvary1, Jianyun Yin1, Hem Nalini Singh1, Gary Pastor1, Vincent Blancuzzi1, Theodore Pellas1, Elizabeth O'Byrne1
1Novartis Pharmaceuticals Corporation, Summit, NJ, USA.
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