This section is the Table 1 of the essay entitled “The promise of melatonin targets/ receptors as therapeutic targets in multiple therapy areas”. It is central to the understanding of the generation of the idea that melatonin does not act solely through receptors and the hypothetical nuclear factor to exert its multiple actions. Neither does it act per se, or only marginally.
The table is a NON-EXHAUSTIVE survey of the literature reporting on the protection afforded by melatonin on multiple models. Most of the models are animal-based, some cellular and a couple a-cellular. The information brought by the table is essentially a collection of keywords that might attract the reader to go directly to the original paper for further details.
As often in the melatonin literature, the concentrations or the amounts of melatonin used are “pharmacological”: i.e. largely beyond micromolar concentrations.
As mentioned above, this list is exemplary of the melatonin situation, not the complete catalog of its actions.
Table 1: Benefits of melatonin throughout the literature